Alok Raghav

Gachon University Korea, South

Dr. Alok Raghav obtained his Ph.D. in Endocrinology from Rajiv Gandhi Centre for Diabetes and Endocrinology, J.N. Medical College, Faculty of Medicine, Aligarh Muslim University, India. He worked as a project scientist at the Indian Institute of Technology in Kanpur, India. He has more than 10 years of research experience in glycobiology and diabetes mellitus. He also worked as Scientist C at the Multidisciplinary Research Unit (sponsored by the Department of Health Research, Ministry of Health and Family Welfare, New Delhi), GSVM Medical College Kanpur, India. He is currently a research professor at the School of Medicine, Department of Anatomy & Cell Biology, Lee Gil Ya Cancer and Diabetes Institute, Gachon University, South Korea. Dr. Raghav has received several international and national awards. He is also an associate editor for Frontiers in Endocrinology and Frontiers in Public Health and an academic editor for PLOS One.

4books edited

3chapters authored

Latest work with IntechOpen by Alok Raghav

Glucose and Insulin Homeostasis provides a thorough overview of the latest research efforts in endocrinology and opens new possible research paths for further novel developments. Chapters address such topics as hypoglycemia in hospitalized patients and those with type 1 diabetes, use of metformin in high-risk patients, the importance of continuous glucose monitoring, lifestyle interventions for managing insulin resistance, and much more.

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Glucose and Insulin Homeostasis

Edited by Alok Raghav

Books edited

By Alok Raghav, Renu Tomar and Jamal Ahmad

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) is severely affecting the worldwide population. It belongs to the coronavirus family which exhibit protein constituted enveloped single-stranded RNA. These viral proteins undergo post-translational modifications (PTMs) that reorganized covalent bonds and modify the polypeptides and in turn modulate the protein functions. Being viral machinery, it uses host cells system to replicate itself and make their copes, their proteins are also subject to PTMs. Glycosylation, palmitoylation of the spike and envelope proteins, phosphorylation, of the nucleocapsid protein are among the major PTMs responsible for the pathogenesis of the viral infection phase. The current knowledge of CoV proteins PTMs is limited and need to be exploring for to understand the viral pathogenesis mechanism and PTMs effect of infection phase.

Part of the book: Fundamentals of Glycosylation

Introductory Chapter: Glimpses of Glycosylation

By Alok Raghav and Jamal Ahmad

Part of the book: Fundamentals of Glycosylation

Estimation of HbA1c and Impact of Continuous Glucose Monitoring in Hypoglycemic States

By Brijesh Kumar Mishra, Alok Raghav, Goo-Bo Jeong, Mukesh Jain, Pinky Shukla and Swati Sharma

Glycosylated hemoglobin (HbA1c) is formed when glucose combines with hemoglobin present in red blood cells making it glycated. Hypoglycemia is presented by less sugar binding with the hemoglobin compared to in hyperglycemia. HbA1c is considered to be a gold standard for measuring glycemic index in diabetic patients. This indicates the burden of blood glucose in subjects with diabetes mellitus. As the normal life span of red blood cells (RBCs) is 90–120 days, therefore HbA1c predicts the average glucose level of 90 days period. Currently, it is being used to combat the burden of diabetes worldwide. There are several cost-effective and high sensitivity & specificity techniques that are being used for the measurement of HbA1c. Most advanced methods include HPLC and enzyme-based. However, there are some variants of hemoglobin that interfere with it. As this is one of the essential parameters to study the progression of diabetes in a patient, a cost-effective and reliable method is required for the estimation.

Part of the book: Glucose and Insulin Homeostasis